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  • Writer's pictureNan Zhang

Collaboration with Prof. Wenxin Wang on Science Foundation Ireland (SFI) Project

Congratulations to Dr Nan Zhang, as project co-applicant, succesfully granted a Science Foundation Ireland (SFI) project titled Harnessing Gene Editing to Treat Rare Diseases such as Epidermolysis Bullosa (EB).

Left to right: Dr. Irene Lara-Sáez, Dr. Nan Zhang, Prof. Wenxin Wang, Mr. Jonathan O’Keeffe Ahern

Dr Nan Zhang, as a co-applicant, is closely working with Prof. Wenxin Wang from UCD Charles Institute of Dermatology, UCD School of Medicine on gene therapy for EB.


Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare genetic skin fragility and blistering disorder in which no curative treatment currently exists with palliative care only in use.


Our proposed solution is to develop a gene editing curative treatment that can be applied topically to wound sites of RDEB patients.

This therapeutic approach will enable the permanent correction of the underlying mutations that give rise to RDEB, in a non-invasive manner.

Project Lead

Prof. Wenxin Wang, Charles Institute of Dermatology, School of Medicine, University College Dublin

Project Co-applicant

Dr Nan Zhang, School of Mechanical and Materials Engineering, University College Dublin

More information can be found from Science Foundation Ireland website here.

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